What Is Semax? The ACTH-Fragment Peptide Explained
Semax is a synthetic peptide developed in Russia from a fragment of the hormone ACTH, sold for laboratory research use only. Here is what it is and how to verify a COA.
Semax is a synthetic peptide originally developed in Russia, based on a fragment of the hormone ACTH. It is a seven-amino-acid peptide and is commonly sold both as plain Semax and as the modified N-Acetyl Semax Amidate.
Research-use status
Semax combines the ACTH(4-7) fragment with an added Pro-Gly-Pro sequence. Much of the published literature on it is animal work from Russian institutions, and this page does not summarise effects or uses.
Semax versus N-Acetyl Semax Amidate
Vendors often sell a modified version, N-Acetyl Semax Amidate, which is engineered to be more stable and longer-acting than plain Semax. These are related but not identical, so confirm which form a product is before comparing prices or COAs.
What to check on a Semax COA
Confirm a named lab, identity by mass spectrometry, HPLC purity with decimals, the exact form (plain versus N-Acetyl Amidate), a matching batch, and a recent date.
Frequently Asked Questions
What is the difference between Semax and N-Acetyl Semax Amidate?
N-Acetyl Semax Amidate is a modified, more stable and longer-acting version of Semax. They are related compounds; confirm which one a vendor sells.
Is Semax approved in the US?
Semax is not an FDA-approved drug in the US and is sold as a research compound. Nothing here is medical advice.
How is Semax verified on a COA?
By mass spectrometry for identity and HPLC for purity, reported by a named lab, with the specific form clearly identified.