What Is Sermorelin? The GHRH Fragment Explained
Sermorelin is a synthetic 29-amino-acid GHRH analog sold for laboratory research use only. Here is what it is, how it compares to CJC-1295, and what to check on a COA.
Sermorelin is a synthetic peptide corresponding to a fragment of growth hormone releasing hormone (GHRH). It corresponds to the first 29 amino acids of GHRH and has a long history in the clinical literature.
Research-use status
Sermorelin is sold for laboratory research use only, and this page does not summarise effects or uses. It has been studied clinically for longer than many newer secretagogues, and is sometimes used as a reference point when comparing GHRH analogs like CJC-1295.
Sermorelin versus CJC-1295
Both are GHRH analogs, but they differ in stability and duration. CJC-1295 (especially with DAC) is engineered to last far longer, while Sermorelin is shorter-acting. Confirm which compound a vendor is selling, since they are not interchangeable.
What to check on a Sermorelin COA
Look for a named lab, mass-spec identity, HPLC purity with decimals, a matching batch, a recent date, and endotoxin testing for injectable research preparations.
Frequently Asked Questions
Is Sermorelin the same as CJC-1295?
No. Both are GHRH analogs, but Sermorelin is shorter-acting while CJC-1295 (especially with DAC) is engineered to last much longer.
Is Sermorelin a growth hormone?
No. It is a 29-amino-acid GHRH analog; growth hormone itself is a 191-amino-acid protein.
What should a Sermorelin COA include?
A named lab, mass-spec identity, HPLC purity with decimals, a matching batch, and a recent date.