What Is TB-500? The Thymosin Beta-4 Fragment Explained
TB-500 is a synthetic peptide based on a region of Thymosin Beta-4, sold for laboratory research use only. Here is what it is and how to verify a COA.
TB-500 is a synthetic peptide based on an active region of Thymosin Beta-4, a naturally occurring 43-amino-acid protein that binds actin. It is sold for laboratory research use only.
Research-use status
TB-500 corresponds to the actin-binding region of Thymosin Beta-4. Published literature on it is mostly animal and cell work, and this page does not summarise effects or uses. It is frequently sold alongside BPC-157, including as a pre-mixed blend, though they are distinct compounds.
TB-500 versus Thymosin Beta-4
TB-500 is not identical to full Thymosin Beta-4; it corresponds to a specific fragment of that protein. When comparing vendor products, confirm what is actually being sold, since some products are labeled TB-500 and others as full-length Thymosin Beta-4.
What to check on a TB-500 COA
A credible COA names the testing lab, confirms identity by mass spectrometry, reports HPLC purity with decimal precision, and ideally includes endotoxin testing for injectable research preparations. Match the batch and confirm a recent test date.
Frequently Asked Questions
Are TB-500 and BPC-157 the same?
No. They are different peptides that vendors often sell together. BPC-157 is a gastric-derived peptide fragment; TB-500 is based on a region of Thymosin Beta-4.
Is TB-500 approved for human use?
No. TB-500 is sold as a research compound only and is not an approved therapeutic. Nothing here is medical advice.
How do I verify a TB-500 COA?
Confirm a named lab, mass-spec identity, HPLC purity with decimals, a matching batch, and a recent date, with a verification key where the lab supports one.